Download dbNSFP for Academic Use
dbNSFP is free for academic and non-commercial use under the CC BY-NC-ND 4.0 license. Please complete the academic user registration to receive your access code and the download instructions.
Registered academic users can also request to re-download the current academic branch of dbNSFP here using your access code going forward.
dbNSFP data format
dbNSFP includes per-chromosome files bundled with the search_dbNSFP Java program, which can search mutations in various formats.
We maintain a stable file format across dbNSFP versions, requiring minimal changes for existing tools and systems to upgrade to the current version of dbNSFP.
We also provide dbNSFP data as a BGZF format file ready for use with Ensembl VEP CLI and SnpSift.
Use dbNSFP Web Service
We provide a web service for querying variant and browsing dbNSFP data without the need to download.
Registered academic users can access this service using the Access Code sent in the confirmation email following academic user registration.
Prospective commercial users can also explore the dbNSFP commercial branch data using web service after applying for a free trial.
Commercial Use of dbNSFP
License fees apply for using dbNSFP in monetized products and services. This model ensures the continued development and maintenance of dbNSFP resources for both academic and industry users. Prospective commercial users should review our commercial use policy and submit the the license application form.